ProtocolPulse

CT/MRI Whole Spine — MSCC [INPATIENT]

CT/MRI
NICE NG2342023 (Replaces CG75)v2.0 · March 2026
Within 24 hours
Inpatient
Open in NICE

Indications — in known cancer patient

— ANY of the following

  • New or progressive back pain (especially thoracic, nocturnal, or unremitting)
  • Neurological signs: weakness, sensory loss, bladder/bowel dysfunction, gait disturbance
  • Any cancer patient with unexplained progressive spinal pain and neurological symptoms

Imaging requirements

— ALL of the following must be met

  • MRI of WHOLE SPINE: sagittal T1 and/or STIR plus sagittal T2 and axial through significant abnormalitiesNICE NG234 Rec 1.5.5
  • Must include ENTIRE spine — not just symptomatic regionNICE NG234 Rec 1.5.4
  • Do NOT perform plain radiographyNICE NG234 Rec 1.5.9
  • If MRI contraindicated: CT with contrastNICE NG234 Rec 1.5.7

Notes

Alert

Contact MSCC coordinator urgently

NICE NG234 Rec 1.3.2
Warning

Do NOT perform plain radiography to diagnose or exclude MSCC

Information

CG75 (2008) fully superseded by NG234 (2023)

Modality Preference

MRI preferred. MRI is first-line for MSCC — CT only if MRI contraindicated

Source: NICE NG234 Rec 1.5.5

Guideline Corrections

CG75 NG234 (2023)

CG75 fully superseded by NG234 in 2023

Change Log

v2.02026-03-08New protocol — metastatic spinal cord compression. References NG234 (replaces CG75).

Not clinical advice. This protocol is a reference tool only. All imaging justifications remain the clinical and legal responsibility of the authorising practitioner under IR(ME)R 2017 (as amended 2024). Protocol content should be verified against current NICE, RCR, and specialty guidelines before use in practice.

AI-assisted content. Clinical criteria were developed with AI assistance and cross-referenced against cited source guidelines. Verify against original sources. Guidelines referenced are current at the stated version date and may have been updated since.