ProtocolPulse

CT Head — Stroke: Non-Thrombolysis / Thrombectomy

CT
NICE NG1282019, updated 2022 (Replaces CG68)v2.0 · March 2026
Immediate
ED
All imaging requests must be justified by an IR(ME)R practitioner (radiologist or radiographer)
Open in NICE

Required Assessment Tools

REQUIRED
ROSIER

Recognition of Stroke in the Emergency Room — clinical assessment tool for suspected stroke

>0 = stroke suspected; ≤0 = stroke less likely (but not excluded — clinical judgement applies)

Immediate CT

Immediate

— ANY of the following

  • ROSIER score >0 (score ≤0 = stroke less likely but not excluded)NICE NG128
  • GCS <13
  • Progressive or fluctuating symptoms
  • Papilloedema, neck stiffness, or fever
  • Severe headache at onset
  • Indication for early anticoagulation
  • Potentially eligible for thrombectomy

Thrombectomy pathway

Immediate

CTA immediately following initial CT; imaging pathway depends on time from onset

  • CTA immediately following initial CT
  • Anterior circulation LVO <6 hours
  • Up to 24 hours with CTP mismatch
  • CTP when >6 hours from onset

Notes

Information

CTA immediately after NCCT if thrombectomy considered

Information

CTP required >6 hours from onset

Information

CG68 fully superseded — remove all references

NICE NG128
Radiation Dose

CT head ~2 mSv; CTA head/neck ~3–5 mSv; CTP ~2–5 mSv

Guideline Corrections

CG68 NG128 (2019, updated 2022)

CG68 fully superseded by NG128

Change Log

v1.02026-03-05Initial publication
v2.02026-03-08CG68 correction added. Thrombectomy 24-hour advanced imaging pathway confirmed.

Not clinical advice. This protocol is a reference tool only. All imaging justifications remain the clinical and legal responsibility of the authorising practitioner under IR(ME)R 2017 (as amended 2024). Protocol content should be verified against current NICE, RCR, and specialty guidelines before use in practice.

AI-assisted content. Clinical criteria were developed with AI assistance and cross-referenced against cited source guidelines. Verify against original sources. Guidelines referenced are current at the stated version date and may have been updated since.