ProtocolPulse

CT/MRI Hepatobiliary & Pancreas

CT/MRI
NICE NG852018NICE NG1042018, updated 2020NICE CG1882014EASL Clinical Practice Guidelines (2018)RCR iRefer2017, continuously updatedv2.0 · March 2026
Varies
OutpatientInpatient
All imaging requests must be justified by an IR(ME)R practitioner (radiologist or radiographer)
Open in NICE

Pancreatic cancer (NG85)

— ANY of the following

  • Pancreatic protocol CT BEFORE draining bile duct for obstructive jaundiceNICE NG85 Rec 1.1.1
  • Pancreatic protocol CT for pancreatic abnormalities without jaundiceNICE NG85 Rec 1.1.4
  • CT CAP for newly diagnosed pancreatic cancerNICE NG85 Rec 1.3.1
  • FDG PET-CT for localised disease receiving treatmentNICE NG85 Rec 1.3.2
  • Pancreatic protocol = arterial + portal venous, thin-section

Acute pancreatitis (NG104)

NG104 focuses on management, NOT diagnosis — guideline gap. UK practice: CT at 48–72 hours for severity/complications. Early CT (<48 hours) may underestimate necrosis.

  • NG104 focuses on management, NOT diagnosis — guideline gap for imaging indicationNICE NG104
  • UK practice: CT at 48–72 hours for severity assessment and complications
  • Early CT (<48 hours) may underestimate necrosis

Bile duct stones — MRCP (CG188)

— ANY of the following

  • Consider MRCP if USS shows no CBD stones but duct dilated and/or LFTs abnormalNICE CG188 Rec 1.1.2
  • Consider EUS if MRCP non-diagnosticNICE CG188 Rec 1.1.3

Liver lesion characterisation

— ANY of the following

  • No standalone NICE guideline — RCR iRefer (guideline gap)
  • Contrast-enhanced MRI with hepatobiliary agent (gadoxetic acid/Primovist) gold standard
  • LI-RADS classification for at-risk patients
  • EASL Clinical Practice Guidelines 2018 for HCCEASL 2018

Notes

Information

Pancreatic protocol = arterial + portal venous phase, thin-section

Information

MRI with hepatobiliary contrast agent gold standard for liver lesions

Warning

Early CT in pancreatitis (<48 hours) may underestimate necrosis

Guideline Corrections

NG188 CG188 (2014)

References to 'NG188' for gallstone disease are incorrect — correct is CG188

Change Log

v2.02026-03-08New protocol — hepatobiliary and pancreatic imaging consolidated

Not clinical advice. This protocol is a reference tool only. All imaging justifications remain the clinical and legal responsibility of the authorising practitioner under IR(ME)R 2017 (as amended 2024). Protocol content should be verified against current NICE, RCR, and specialty guidelines before use in practice.

AI-assisted content. Clinical criteria were developed with AI assistance and cross-referenced against cited source guidelines. Verify against original sources. Guidelines referenced are current at the stated version date and may have been updated since.